In 1918, Elizabeth MacDonald learns that her husband, John Andrew, has been killed in the war. Elizabeth bears John's son and eventually marries her kindly boss. Unknown to her, John has survived but is horribly disfigured and remains in Europe. Years later, on the eve of World War II, Elizabeth refuses to agree to her son's request to enlist and is stunned when an eerily familiar stranger named Kessler arrives from abroad and becomes involved.

Roger Hudson, a wealthy businessman who has moved to Washington to work for the government as a "dollar a year man," is late for a radio broadcast about his new department, the Mobilization of Woman Power for War. He takes a cab driven by Dixie Dugan, who hopes that being a cabbie while the country's men are away fighting will help the war effort. Her incompetent driving, however, results in an accident for which Roger must take responsibility in order to reach the radio station in time. Dixie then returns home, where she lives with her father Timothy, who is constantly practicing his air raid warden duties, her mother Gladys, an aspiring Red Cross worker, and cousin Imogene, who studies incessantly to become a "quiz kid." The Dugans rent out their spare rooms to Dixie's fiancé, Matt Hogan, and to blustering Judge J. J. Lawson. Matt, who works in a munitions factory, wants Dixie to settle down and marry him, but Dixie is determined to help her country.

Berle plays a mystery writer who forever writes himself into corners and is never able to finish a story. While visiting his wife (Mary Beth Hughes) at the office where she works, Berle overhears several men discussing the suicide of a coworker. Struck with a brilliant notion, Berle decides to confess to the murder of the dead man, certain that he'll be able to wriggle out of the situation and thereby have plenty of material for a story.

Nightclub owner Steve Larwitt sees his empire of investments collapse as he faces tax evasion charges and attacks by rivals. Believing Steve will be safer in prison for one year, his wife, Brenda, testifies against him on advice from his lawyer, Slant Kolma, who is in love with her. After Steve receives 10 years in Alcatraz, Brenda moves to be near him and avoids advances of airplane builder Tim Nolan, who knows nothing about her past.

An innocent man is bamboozled into trading places with a dangerous escaped convict.

Ballet star Petrov arranges to cross the Atlantic aboard the same ship as the dancer and musical star he's fallen for but barely knows. By the time the ocean liner reaches New York, a little white lie has churned through the rumour mill and turned into a hot gossip item—that the two celebrities are secretly married.

In the underworld of Manhattan, a woman dares to stand up to one of the city's most powerful gangsters.

City girl marries country doctor, meets prejudice and exclusion when she tries to befriend the townspeople.

Dr. Socrates gave up his brilliant career as surgeon in a prominent hospital because his betrothed died under his knife. He is now a struggling doctor in a small town that has a gangster's hideout.

Bob Hope wants to marry the mayor's daughter, but the mayor doesn't want his daughter to marry Bob Hope.