The story of the legendary wits who lunched daily at the Algonquin Hotel in New York City during the 1920s. The core of the so-called Round Table group included short story and poetry writer Dorothy Parker; comic actor and writer Robert Benchley; The New Yorker founder Harold Ross; columnist and social reformer Heywood Broun; critic Alexander Woollcott; and playwrights George S. Kaufman, Marc Connelly, Edna Ferber and Robert Sherwood.

Penny Morris and Tommy Williams are both starstruck young teens but nobody seems to give them any chance to perform. Instead, they decide to put up their own show to collect money for a summer camp for the kids.

Cécile, Annette, Yvonne, Émilie and Marie, the Dionne Quintuplets, turn five years old and have a private birthday party in their garden. Other than the five little French-Canadian princesses-of-the-world, the attendees at the party for the sheltered sisters are their doctor-and-mentor Roy Dafoe; a priest and two nurses; radio's "Town Crier" Alexander Woollcott; and RKO-Newsreel cameraman Harry Smith.

A ruthless, cynical, hated publisher is killed in a plane crash, doomed to be a "restless" spirit for being unloved. A heavenly power gives him a month on Earth to find one person to shed a tear for him before his fate is sealed.

Conceited radio announcer irritates everyone else at the station.

As the rather fussy 'Mr. W' is dining in a restaurant, the waiter introduces him to an attractive woman, who sits down at his table. She asks him to take her to the theater, but he declines, indicating that he would prefer to relax at the restaurant. To entertain her, he teaches her a word game called the 'Minute Game'.