Fictional documentary about the life of human chameleon Leonard Zelig, a man who becomes a celebrity in the 1920s due to his ability to look and act like whoever is around him. Clever editing places Zelig in real newsreel footage of Woodrow Wilson, Babe Ruth, and others.

Four panelists must determine guests' occupations - and, in the case of famous guests, while blindfolded, their identity - by asking only "yes" or "no" questions.

The scene is set at Billy Rose's Casa Manana Revue, filmed at the Fort Worth Frontier Fiesta (1937), an enormous production created as part of the Texas Centennial civic celebrations. The opening song, "The Night Is Young And You're So Beautiful" emanated from the first edition of the Revue and became a hit song on two continents in 1936.