Roberta is a bored suburban housewife who is fascinated with a woman, Susan, she only knows about by reading messages to and from her in the personals section of the newspaper. This fascination reaches a peak when an ad with the headline "Desperately Seeking Susan" proposes a rendezvous. Roberta goes too, and in a series of events involving amnesia and mistaken identity, steps into Susan's life.

A New York City cop and an expert criminologist trying to solve a series of grisly deaths in which the victims have seemingly been maimed by feral animals discover a sinister connection between the crimes and an old legend.

The life of boxer Jake LaMotta, whose violence and temper that led him to the top in the ring destroyed his life outside of it.

A famous fashion photographer develops a disturbing ability to see through the eyes of a serial killer.

A bookish CIA researcher finds all his co-workers dead, and must outwit those responsible until he figures out who he can really trust.

After his wife is murdered by street punks, a pacifistic New York City architect becomes a one-man vigilante squad, prowling the streets for would-be muggers after dark.

Two desperate people have a wonderful romance, but their political views and convictions drive them apart.

A common friend's sudden death brings three men, married with children, to reconsider their lives and ultimately leave the country together. But mindless enthusiasm for regained freedom will be short-lived.

A family of vampires takes over an estate known as Carfax Abbey. Since inbreeding is destroying the family line, they need new blood to keep the family going, so they set out to find new sources.

Joe Buck is a wide-eyed hustler from Texas hoping to score big with wealthy New York City women; he finds a companion in Enrico "Ratso" Rizzo, an ailing swindler with a bum leg and a quixotic fantasy of escaping to Florida.

A cop quits the force after too much disappointment in the system. He becomes a bodyguard of a rich recent widow. She is on trial for her husband's murder. He decides to help her clear her name... and get over her husband.

A married woman pursues an affair with her abusive husband's best friend and tries to keep her secret life going despite her personal life collapsing around her.

Liz is a New York prostitute/model whom tries to go straight by having an affair with a nice guy, named Michael, only to have her employer, Sam, and his mafia connections refuse to let her leave the business.

Mr. Jaffee is a curious but closeted married man, who decides to take a walk on the wild side one night over to the local bath house located in Times Square, New York. When he is a approached by Thomas, a swinging regular who takes an interest in Mr. Jaffe as the new face "on the scene", a deep discussion about marriage, connection and loss begins to unexpectedly unfold. The two become emotionally intimate in a very short time, with no sexual contact of any sort, while everyone around them are screwing like rabbits.

A Jewish pawnbroker, a victim of Nazi persecution, loses all faith in his fellow man until he realizes too late the tragedy of his actions.

An aging doctor's resentment of his young assistant could lead to tragedy.

Gloria Wandrous, a promiscuous fashion model, falls in love with Weston Liggett, the hard drinking son of a working class family who has married into money.