A cross-country road race is based on an actual event, the Cannonball Baker Sea to Shining Sea Memorial Trophy Dash, organized by Brock Yates to protest the 55 mph speed limit then in effect in the U.S. The Cannonball was named for Erwin G. "Cannonball" Baker, who in the roaring 20's rode his motorcycle across the country. Many of the characters are based on ruses developed by real Cannonball racers over the several years that the event was run.

Handsome Stranger has agreed to escort Charming Jones to collect her inheritance from her father. But Avery Simpson wants the money and hires notorious outlaw Cactus Jack to ambush Charming. However, Cactus Jack is not very good at robbing people.

Legendary stunt man Sonny Hooper remains one of the top men in his field, but due to too many stressful impacts to the spine and the need to pop painkillers several times a day, he knows he should get out of the industry before he ends up permanently disabled.

A race car driver tries to transport an illegal beer shipment from Texas to Atlanta in under 28 hours, picking up a reluctant bride-to-be on the way.