When their beloved school is threatened with closure should the powers that be fail to raise the proper funds, the girls scheme to steal a priceless painting and use the profits to pull St. Trinian's out of the red.

Drama based on real-life events. Marie Stubbs, a diminutive Glaswegian headmistress who is coming up to retirement age, takes on one last challenge: to improve the fortunes of St George's School in north west London which was facing closure after the notorious murder of its previous headmaster, Philip Lawrence, in 1995 as he was breaking up a fight between his pupils and those from a rival school.