In 1931, budding author Christopher Isherwood goes to Berlin at the invitation of his friend W. H. Auden for the gay sex that abounds in the city. He falls for street sweeper Heinz, paying medical bills for the boy's sickly mother, to the disapproval of her other son, Nazi Gerhardt.

An independent, single mother who owns a small hotel on a Greek island is about to marry off the spirited young daughter she's raised alone. But, the daughter has secretly invited three of her mother's ex-lovers in the hopes of finding her biological father.

Set during the 1960s in the fictional North Yorkshire village of Aidensfield, this enduringly popular series interweaves crime and medical storylines.