Glenn Manning, "The Amazing Colossal Man," believed dead after falling from the Hoover Dam, reemerges in rural Mexico, brain damaged, disfigured, and very angry.

Gladys Glover has just lost her modeling job when she meets filmmaker Pete Sheppard shooting a documentary in Central Park. For Pete it's love at first sight, but Gladys has her mind on other things, making a name for herself. Through a fluke of advertising she winds up with her name plastered over 10 billboards throughout city.