Middle-aged newlyweds Larry & Barbara spend their honeymoon at a palatial Caribbean mansion, unaware that it is inhabited by the vengeful spirit of a notorious voodoo witch queen who was murdered a century ago. The woman's evil spirit promptly begins precipitating a variety of violent deaths in accordance with a diabolical ritual intended to bring her back to life -a process which is ultimately consummated by taking possession of Barbara's body.

Poe's fiance, Lenore, falls into a coma and is taken for dead. She is rescued at the last possible moment from being buried alive, but the experience has driven her insane. On the advice of his friend, Dr. Forrest, Poe commits Lenore to the asylum run by Dr. Grimaldi. On a visit to the asylum, Poe and Forrest sense that something strange is going on, and decide to sneak back in after dark and investigate.

Leaving the poverty of his life in Shantung to seek fortune in Shanghai, The Boxer is instead drawn into a world of corruption, gang warfare and evil... Where his only protection is his famed fighting technique.