In the panicky, uncertain hours before his wedding, a groom with prenuptial jitters and his two best friends reminisce about growing up together in the middle-class African-American neighborhood of Inglewood, California. Flashing back to the twenty-something trio's childhood exploits, the memories capture the mood and nostalgia of the '80s era.

A successful physician and devoted family man, John Dolittle seems to have the world by the tail, until a long suppressed talent he possessed as a child, the ability to communicate with animals is suddenly reawakened with a vengeance! Now every creature within squawking distance wants the good doctor's advice, unleashing an outrageous chain of events that turns his world upside down!