Highway Patrol was a syndicated, fictional police action series produced from 1955 to 1959, concerning the activities of the highway patrol and their leader, Dan Matthews (who held no rank). Although filmed in and around the Los Angeles area, the state setting for the stories was never identified, and city and street names were fictionalized.

Night riders are terrorizing homesteaders, and the town doctor tries to keep the locals from forming a vigilante group. After more towns people are killed, however, the rest of the town makes the doctor the town sheriff and tells him to clean up the gang.