When six sorority sex kittens hook up for a night of carefree indulgence during spring break, they have no idea that maniacal serial killer Stanley Peterson (Curtis Taylor) has escaped from a nearby prison and is now on the prowl for fresh blood. Can they stop the madman before he notches up another half-dozen deadly conquests?

Death is no stranger to Zeta house, where events surrounding a panty raid gone awry have become the stuff of legend. Now, more than 20 years later, death is in the air again as five Zeta girls set up summer residence off-campus.

Sarah McKinnis, a software engineer at a weapons factory, is accidentally shot in the head by a new type of riot control pistol. From that moment, her life becomes a nightmare. People appear to her as hideous aliens but she's the only one that can see these creatures. She tries to warn her normal looking supervisor, Ed Devon, but the evil space creatures massacre everyone at her laboratory. Sarah escapes with the pistol. The aliens kill her sister in retaliation. She wages a lone war against the extra-terrestrial menace, shooting and killing the army of hideous, green skinned monsters from space. But, how can one woman stop this hidden invasion from the stars?