An ex-felon is shocked to see just how much the world has changed when he is released from prison for good behavior after a 15-year stint and returns to his newly gentrified Brooklyn neighborhood.

Raymond "Red" Reddington, one of the FBI's most wanted fugitives, surrenders in person at FBI Headquarters in Washington, D.C. He claims that he and the FBI have the same interests: bringing down dangerous criminals and terrorists. In the last two decades, he's made a list of criminals and terrorists that matter the most but the FBI cannot find because it does not know they exist. Reddington calls this "The Blacklist". Reddington will co-operate, but insists that he will speak only to Elizabeth Keen, a rookie FBI profiler.

Samantha is recovering from a suicide attempt and ready for a fresh start in life. She has to fight for the custody of her daughter.

A woman stuck in a stale marriage struggles to raise her children and manage her secret drug habit. But when winter comes to her small town, her balancing act begins to come crashing down.

Fresh out of a long stretch in prison, Virgil Bliss (Clint Jordan) vows to go straight in this gritty, character-driven drama. But finding a job, a wife and a sense of purpose doesn't come easy when you're living in a halfway house surrounded by junkies and thugs. Things start to look up when Virgil falls for Ruby (Kirsten Russell), a prostitute and fellow lost soul, but her drug addiction stands in the way of his shot at a normal life.

A forty-year marriage begins to unravel when the husband brings home a pet fish that he wants to keep in the bathtub.

In cases ripped from the headlines, police investigate serious and often deadly crimes, weighing the evidence and questioning the suspects until someone is taken into custody. The district attorney's office then builds a case to convict the perpetrator by proving the person guilty beyond a reasonable doubt. Working together, these expert teams navigate all sides of the complex criminal justice system to make New York a safer place.