Dealing with life's troubles is never easy. Many people find comfort in the soothing words of their trusted therapist. Mr. Talbot does not. His therapist, has a tough love approach. Not convinced of Talbot's assertion that he's a werewolf, she invites him to her office the evening of the full moon. Talbot insists that he's really dangerous. As the doctor insists Talbot's delusional, suddenly he begins to change. Prepared, Dr. Steiner has no trouble curing her patient. For good.

Adrian Monk was once a rising star with the San Francisco Police Department, legendary for using unconventional means to solve the department's most baffling cases. But after the tragic (and still unsolved) murder of his wife Trudy, he developed an extreme case of obsessive-compulsive disorder. Now working as a private consultant, Monk continues to investigate cases in the most unconventional ways.