A research scientist explores the boundaries and frontiers of consciousness. Using sensory deprivation and hallucinogenic mixtures from native American shamans, he explores these altered states of consciousness and finds that memory, time, and perhaps reality itself are states of mind.

A truck-stop waitress, determined to make a better life for her young children after being abandoned by her husband, leaves hash-slinging behind her to embark on a new career as a trucker in the rig her late father used to drive.