A group of young men agree to act as "test subjects" for plastic surgeon Victoria Franks. But their getaway at Victoria's lavish Malibu mansion turns deadly, as their mad scientist hostess implements a nefarious and homicidal agenda.

Sent to a Gladiator retreat, Hercules frustrates his fellow warriors with his arrogance, but when his rival, Capaneous, schemes to poison Hercules, he must learn humility and devise a plan to survive a wrestling match in his weakened state.