The Herlihys are a working class family from Chicago whose three children take wildly divergent paths: Brian joins the Marines right out of High School and goes to Vietnam, Michael becomes involved in the civil rights movement and after campaigning for Bobby Kennedy and Eugene McCarthy becomes involved in radical politics, and Katie gets pregnant, moves to San Francisco and joins a hippie commune. Meanwhile, the Taylors are an African-American family living in the deep South. When Willie Taylor, a minister and civil rights organizer, is shot to death, his son Emmet moves to the city and eventually joins the Black Panthers, serving as a bodyguard for Fred Hampton.

A day in the life of a Chicago cab driver is examined as he picks up fares from the good and bad parts of the city and emotionally connects to many of his passengers.