A cancer survivor, an amputee, several immigrants, and many others are snatched from a Los Angeles street and forced to take part in a deadly race.

A globe-trotting photojournalist has a secret life as a CIA field agent.

After losing contact with Earth, Astronaut Lee Miller becomes stranded in orbit alone aboard the International Space Station. As time passes and life support systems dwindle, Lee battles to maintain his sanity - and simply stay alive. His world is a claustrophobic and lonely existence, until he makes a strange discovery aboard the ship.

Sara (Amber Jaeger) suffers from agoraphobia, an obsessive fear of open spaces that renders her a virtual captive of her own home. When her husband, Mark (Kieron Elliott), disappears unexpectedly, Sara unravels emotionally and begins to panic. Turning to her estranged sister (Kristine Sullivan) and a psychiatrist (Andrew Qamar) for support, Sara soon begins to wonder whether the doctor is trying to help her or is plotting her demise.