An action comedy centered on Blubberella, an overweight half-vampire woman whose footsteps cause explosions and whose dual swords are used against anyone who makes fun of her. She must face an army of undead Nazi soldiers in her valiant struggle against bloodshed and tyranny.

Rayne fights against the Nazis in Europe during World War II, encountering Ekart Brand, a Nazi leader whose target is to inject Adolf Hitler with Rayne's blood in an attempt to transform him into a dhampir and attain immortality.