Writer Harry Street reflects on his life as he lies dying from an infection while on safari in the shadow of Mount Kilimanjaro.

Horse trainer Shawn O'Hara and his lovely niece, Margaret, come to America to escape the memory of an accident involving Margaret's brother, Danny. Working with thoroughbreds in Kentucky, Shawn takes a liking to a yearling named Seabiscuit, and fights to convince the horse's owner that the tiny horse with big knees will become a top-notch racehorse. Meanwhile, Margaret begins a tentative relationship with jockey Ted Knowles, but is haunted by her brother's death in a steeplechase spill. Written by Ray Hamel