International Security Affairs agent Jon is on a dangerous mission to escort a criminal scientist to another country. En route, a member of his team turns out to be a traitor and shoots Jon in the head while kidnapping the scientist. When Jon wakes up in the hospital, a doctor tells him that within weeks, the bullet in his brain will cause complete paralysis. Jon returns to Beijing to see his mother, who confesses that Jon has a brother in Malaysia who was raised by his father, a gambler. Jon takes a flight to Malaysia to find his brother, Yeung. On the plane he forms a bond with Dr. Kan, who promises to look into possible treatments for his condition. However, when they arrive, Yeung tries to kidnap the doctor and when Jon intervenes, he's also taken hostage. The two soon realize they're brothers, and decide to work together in order to keep the criminals behind the kidnappings from reinfecting the world of a disease long thought cured.

A group of college students book a bargain dream holiday to a remote tropical island, little knowing that they have been lured there by the island's evil owner to fulfill an ancient voodoo prophecy. Soon, what appears to be paradise is transformed as friends and siblings are pitched against each other in a desperate fight for survival. Doubt, suspicion and panic splinter the group as each member begins to fall victim to the terrifying reality of their own worst nightmares. Can those who are left find the strength to confront and overcome the fear that will otherwise be their end, or will the voodoo curse win out?

When a deadly assassin hijacks a passenger train, he threatens to detonate a deadly can of poison that can wipe out an entire city, if he isn't given a 25 million dollar Ransom. While the cops are attempting to thwart the madman, they decide to call Former DEA agent Paul Blake (Antonio Sabato, Jr) the one man who can possibly stop the fiendish plot.