Naples, 1959. Pure Mathematics professor Renato Caccioppoli, Bakunin's grandson, is a tortured soul. Recently discharged from the psychiatric hospital, left by his wife, and increasingly disillusioned with academia and the Communist Party, he lives his last days with painful detachment.

In pre-World War II Sicily, just as the fascists come to power, two men fall in love with the same woman. The changes in their country's politics ultimately take all three on a journey across the ocean to New York City.

Lizzy, a liberated American photographer, falls for narrow-minded journalist Paolo. Then finds she can't live with him or without him.

Pasqualino Frafuso, known in Naples as "Pasqualino Seven Beauties" is a petty thief who lives off of the profits of his seven sisters while claiming to protect their honor at any cost, Pasqualino is arrested for murder and later sent to fight in the army after committing sexual assault. The Germans capture him and he gets sent to a concentration camp where he plots to make his escape by seducing a German officer.