The story of New Jersey-based Italian-American mobster Tony Soprano and the difficulties he faces as he tries to balance the conflicting requirements of his home life and the criminal organization he heads. Those difficulties are often highlighted through his ongoing professional relationship with psychiatrist Jennifer Melfi. The show features Tony's family members and Mafia associates in prominent roles and story arcs, most notably his wife Carmela and his cousin and protégé Christopher Moltisanti.

Seven junior-high-school girls organize a daycare camp for children while at the same time experiencing classic adolescent growing pains.

Fun-loving Annabelle Andrews and her uptight mother, Ellen, have a hard time getting along with each other. One Friday the 13th, they both wear magical necklaces that make them switch bodies for the day.

Fran, fresh out of her job as a bridal consultant in her boyfriend’s shop, first appears on the doorstep of Broadway producer Maxwell Sheffield peddling cosmetics, and quickly stumbled upon the opportunity to become The Nanny for his three children. But soon Fran, with her offbeat nurturing and no-nonsense honesty, touches Maxwell as well as the kids.

After her husband loses his job, Marianne moves from Beverly Hills to a nightmare New York City. She hires ditzy psychic Reva to redecorate her apartment, and they end up being pursued by a crazed killer.

Dramatically presented situations, often controversial, of interest to children and teenagers. Several episodes were either in animated form or presented as documentaries. Topics included illiteracy, substance abuse and teenage pregnancy.