Following the tragic death of her teenage son, Manuela travels from Madrid to Barcelona in an attempt to contact the long-estranged father the boy never knew. She reunites with an old friend, an outspoken transgender sex worker, and befriends a troubled actress and a pregnant, HIV-positive nun.

Lara, the host of a radio call-in show dealing in psychic phenomena, discovers that her gay estranged lover has been found dead in a small Spanish village. She learns that he was conducting secret experiments searching for tortured souls trapped behind the energy of the living world. This leads her to an old, abandoned house where the experiments took place - and there she finds a world of secrets and horror...