A young doctor in a US hospital administers a powerful and untested cocktail of drugs to a coma victim. But instead of curing him, it triggers a powerful "out-of-body" experience and enables the patient - a depraved and dangerous loner - to inhabit other people's bodies and, through them, take revenge on the bullying medical students who were accidentally responsible for his condition.

A minister dispenses justice on three convicts who take his family hostage.