Merel, a single midwife, is done with men, but her biological clock is ticking inexorably. And yes, she gets pregnant. However, the whole family suddenly seems pregnant. Her 60-plus father Piet has just become a father again with his young partner and her 23-year-old niece Eva is also expecting. Annet, Merel's older sister, who suffers from the empty nest syndrome, has a husband Theo who only wants to travel because he thinks is too young to become a grandfather.

Youssef, a professional liar, falls in love with airhead waitress Andrea. Things get awry as she never wants to date a guy who keeps secrets or lies.

Former Amsterdam police detective Floris Wolfs has been transferred to the police department of the south-Dutch country town Maastricht. His metropolitan experience nicely complements the local expertise of his new country colleagues, who know the folks. Slowly he fits in, while solving countless crimes together with his female partner Eva van Dongen.