The Affair explores the emotional effects of an extramarital relationship between Noah Solloway and Alison Lockhart after the two meet in the resort town of Montauk in Long Island. Noah is a New York City schoolteacher with one novel published (book entitled A Person who Visits a Place) and he is struggling to write a second book. He is happily married with four children, but resents his dependence on his wealthy father-in-law. Alison is a young waitress trying to piece her life and marriage back together in the wake of the tragic death of her child. The story of the affair is told separately, complete with distinct memory biases, from the male and female perspectives.

Brandon, a thirty-something man living in New York, eludes intimacy with women but feeds his deepest desires with a compulsive addiction to sex. When his younger sister temporarily moves into his apartment, stirring up bitter memories of their shared painful past, Brandon's life, like his fragile mind, gets out of control.

Mona Gray is a 20-year-old loner who, as a child, turned to math for salvation after her father became ill. As an adult, Mona now teaches the subject and must help her students through their own crises.

A car magnate watches his personal and professional life hit the skids because of his business and romantic indiscretions.

Armed men hijack a New York City subway train, holding the passengers hostage in return for a ransom, and turning an ordinary day's work for dispatcher Walter Garber into a face-off with the mastermind behind the crime.

Lipstick Jungle is an American comedy-drama television series created by DeAnn Heline and Eileen Heisler for NBC Universal Television Studio. The hour-long series was based on the best-selling novel of the same name by Candace Bushnell, who also served as executive producer alongside showrunner/head writer Oliver Goldstick. The pilot was directed by Gary Winick.