A small town teenager in the 1960s believes her dreams of becoming a famous singer will come true when her rock star idol gets stranded in town. But a leak in a nearby chemical plant that is believed to be causing mass mutations threatens to turn her dream into a nightmare.

Griffin Conner, a med-school dropout having left in a haze of disgrace, is forced to return to Bethune General Hospital as its newest orderly and work alongside his family.

Set in the 1950s, a a group of young girls in upstate New York form their own gang.