Syd March is an employee at a clinic that sells injections of live viruses harvested from sick celebrities to obsessed fans. When he becomes infected with the disease that kills super sensation Hannah Geist, Syd becomes a target for collectors and rabid fans. He must unravel the mystery surrounding her death before he suffers the same fate.

Major real-life air disasters are depicted in this series. Each episode features a detailed dramatized reconstruction of the incident based on cockpit voice recorders and air traffic control transcripts, as well as eyewitnesses recounts and interviews with aviation experts.

Twitch City is a surreal sitcom set in the Toronto, Ontario neighbourhood of Kensington Market, and follows Curtis, a television addict who refuses to leave his apartment, and his friends and roommates Nathan and Hope. In the series' first episode, Nathan is sent to prison for killing a homeless man with a can of cat food, leaving Curtis and Hope to find a replacement roommate to help with the rent.