The unit specializes in the investigation of serial murders and is led by Van der Bijl, a former murder and robbery detective who gained fame for his handling of several high-profile cases. Each episode focuses on a serial killer. The main character, Colonel Piet van der Bijl, also known as Die Byl, is loosely modeled on the famous ex-detective Piet Byleveld.

After engaging in an illicit affair with one of his pupils, teacher Parker Sithole spirals into an abyss of obsession that eventually turns to murder. A cinephile's passionate homage to classic film noir, Of Good Report is a serial killer origins story about how a social misfit turns into an inadequate man hellbent on satisfying his shameful lust. It is Little Red Riding Hood, told from the wolf's perspective.

Madam & Eve is a South African television sitcom based on the comic strip Madam and Eve created by S. Francis, H. Dugmore and Rico which takes a humorous look at the unique relationship between two South African women as they reach out to each other – across the kitchen – in the new South Africa.