The Catholic Church secretly investigates Caravaggio as the Pope weighs whether to grant him clemency for killing a rival.

Valentino Tarocco invents a new life as a famous Milanese designer. He has removed all connection with the past, but an accident will bring him back to his twenties, causing him to recover his Apulian dialect and love for his origins.

Now in the Far North (i.e. Milan!), Alberto has accepted to manage a program for efficiency improvement in the Italian Post. He devotes all his time and all his energy to this noble task and neglects his wife Silvia, which of course annoys her beyond limits. Things do not fare much better in Castellabate where it is rather Maria, Matta's wife, who gets on his nerves by always blaming him for his lack of ambition. One day, due to a misunderstanding, Mattia is transferred to... Milan! And on whose doorstep does he land? Alberto's of course!

Marco Ferretti is an Italian manager who is young and beautiful, but he cannot stand the presence of women after a difficult affair. When Marco goes to London for an appointment, he meets four beautiful girls who disrupt his life with love.

The film follows Nello, the recently hired director of a newly developed work cooperative of former mental patients. After the closure of state psychiatric hospitals and asylums in Italy under the Basaglia Law many former patients were left with few resources and little hope of reintegrating into society. With the intention of actually improving the lives of his pupils, rather than just sedating them, Nello encourages them to expand their individual abilities and explore the wider world around them although, regardless of intention, there is sometimes a price to pushing boundaries too quickly.

With very weak health and wait for the police to evict the immigrants occupying the building Pantanella Luigi remembers working in the mines of Belgium, along with Italian immigrants, their allocation to Giano, a suburb where subhuman living conditions provoke wars among the indigent, his work at Caritas, creating homeless shelters, first aid to AIDS patients, their struggle for racial and religious integration ... and above all, lack of support from different political parties and leaders of the church itself.

Policewoman Anna Mari is forced to play a dangerous game with the title serial killer. If she loses, she witnesses the maniac's tortured victims having their throats cut in explicit close-up detail via webcam. She teams up with British cop John Brennan to find out the identity of the murderer.

The adventures and mis-adventures of a group of co-workers are shown by a camera on top of the coffee-machine in the relax area.