John Travolta is a downtrodden single father raising his daughter under difficult circumstances in Chicago. The young girl comes upon and then nurses a wounded Doberman used for fighting, back to health. Duped by underworld types he was working as a courier for, father and daughter leave the dog and flee cross-country to Los Angeles with both canine and mobsters in pursuit.

A kid from the neighborhood goes to work for the Mafia as a collector.