Ace is an impressionable young man working for a dry cleaning business. His friend, drug dealer Mitch, goes to prison. In an unrelated incident, he finds some cocaine in a pants pocket. Soon, Ace finds himself dealing cocaine for Lulu. Via lucky breaks and solid interpersonal skills, Ace moves to the top of the Harlem drug world. Of course, unfaithful employees and/or rivals conspire to bring about Ace's fall.

An unsuspecting, disenchanted man finds himself working as a spy in the dangerous, high-stakes world of corporate espionage. Quickly getting way over-his-head, he teams up with a mysterious femme fatale.

In the 1920s, the rights of American workers to join a labor union was still considered an open question, and African-Americans were routinely denied their civil and economic rights. 10,000 Black Men Named George, the title, refers to the fact Pullman porters were often called "George" by white passengers, which was considered a racial slur.