Upon waking up to the news that the man she’d gone on a date with the previous night has been murdered, a young woman with only a faint memory of the night’s events begins to suspect that she murdered him while attempting to resist his advances.

Father O'Malley is sent to St. Mary's, a run-down parochial school on the verge of condemnation. He and Sister Benedict work together in an attempt to save the school, though their differing methods often lead to good-natured disagreements.

Suburban Paradise Park becomes a heaven for social-minded Mrs. Alice Summers (Mary Boland), when she accidentally causes the apprehension of two bank robbers after walking into the bank during the robbery and one of the robbers, in taking money from her purse, left his fingerprints on the purse. She is made an honorary police captain and, with her society sisters sets about "keeping lawlessness" out of the town. From that point on, life becomes miserable for her hen-pecked husband Calvin (Ernest Truex).

A crooked real estate manipulator sells worthless land on mortgage to flood refugees, then tries to profit by reselling the land to the state, committing murder in the process, as the Three Mesquiteers work to bring him and his gang to justice.