The story of New Jersey-based Italian-American mobster Tony Soprano and the difficulties he faces as he tries to balance the conflicting requirements of his home life and the criminal organization he heads. Those difficulties are often highlighted through his ongoing professional relationship with psychiatrist Jennifer Melfi. The show features Tony's family members and Mafia associates in prominent roles and story arcs, most notably his wife Carmela and his cousin and protégé Christopher Moltisanti.

Based on the bestselling book by Candace Bushnell, Sex and the City tells the story of four best friends, all single and in their late thirties, as they pursue their careers and talk about their sex lives, all while trying to survive the New York social scene. 

ER explores the inner workings of an urban teaching hospital and the critical issues faced by the dedicated physicians and staff of its overburdened emergency room.

Siblings Ethan and Hallie O'Fallon plot to get their divorced parents back together in time for Christmas.

In cases ripped from the headlines, police investigate serious and often deadly crimes, weighing the evidence and questioning the suspects until someone is taken into custody. The district attorney's office then builds a case to convict the perpetrator by proving the person guilty beyond a reasonable doubt. Working together, these expert teams navigate all sides of the complex criminal justice system to make New York a safer place.

D.E.A. is a short-lived television program which was aired by Fox Broadcasting Company as part of its 1990-91 lineup. D.E.A. was based on true stories of the Drug Enforcement Administration. Shot in cinéma vérité style, the program combined recreated scenes using actors with actual surveillance footage and film of actual newscasts covering the stories depicted. Fox apparently had considerable confidence in this concept. When the initial version garnered low ratings and was put on hiatus, before its return the program was retooled into DEA—Special Task Force, which placed more emphasis on the agents' personal lives and showed less graphic violence. The revamped show premiered in April 1991, but also failed to achieve significant ratings and the program was canceled for good in June 1991.

Murphy Brown (Candice Bergen) is a recovering alcoholic who returns to the fictional newsmagazine FYI for the first time following a stay at the Betty Ford Clinic residential treatment center. Over 40 and single, she is sharp tongued and hard as nails. In her profession, she is considered one of the boys, having shattered many glass ceilings encountered during her career. Dominating the FYI news magazine, she is portrayed as one of America's hardest-hitting (though not the warmest or more sympathetic) media personalities.

Thirtysomething is an American television drama about a group of baby boomers in their late thirties. It was created by Marshall Herskovitz and Edward Zwick for MGM/UA Television Group and The Bedford Falls Company, and aired on ABC. It premiered in the U.S. on September 29, 1987. It lasted four seasons, with the last of its 85 episodes airing on May 28, 1991. The title of the show was designed as thirtysomething by Kathie Broyles, who combined the words of the original title, Thirty Something. In 1997, "The Go Between" and "Samurai Ad Man" were ranked #22 on TV Guide′s 100 Greatest Episodes of All Time. In 2002, Thirtysomething was ranked #19 on TV Guide′s 50 Greatest TV Shows of All Time, and in 2013 TV Guide ranked it #10 in its list of The 60 Greatest Dramas of All Time.

L.A. Law is an American television legal drama series that ran for eight seasons on NBC from September 15, 1986, to May 19, 1994. Created by Steven Bochco and Terry Louise Fisher, it contained many of Bochco's trademark features including a large number of parallel storylines, social drama and off-the-wall humor. It reflected the social and cultural ideologies of the 1980s and early 1990s, and many of the cases featured on the show dealt with hot-topic issues such as abortion, racism, gay rights, homophobia, sexual harassment, AIDS, and domestic violence. The series often also reflected social tensions between the wealthy senior lawyer protagonists and their less well-paid junior staff. The show was popular with audiences and critics, and won 15 Emmy Awards throughout its run, four of which were for Outstanding Drama Series.