The story of the early days of Deadwood, South Dakota; woven around actual historic events with most of the main characters based on real people. Deadwood starts as a gold mining camp and gradually turns from a lawless wild-west community into an organized wild-west civilized town. The story focuses on the real-life characters Seth Bullock and Al Swearengen.

Legendary marshal Wyatt Earp, now a weary gunfighter, joins his brothers Morgan and Virgil to pursue their collective fortune in the thriving mining town of Tombstone. But Earp is forced to don a badge again and get help from his notorious pal Doc Holliday when a gang of renegade brigands and rustlers begins terrorizing the town.