Canadian contestants are confronted with 26 sealed briefcases full of varying amounts of cash -- ranging from a measly penny to a million dollars. Without knowing the amount in each briefcase, they pick one -- theirs to keep, if they chooses, until its unsealing at game's end.

Dr. Gregory House, a drug-addicted, unconventional, misanthropic medical genius, leads a team of diagnosticians at the fictional Princeton–Plainsboro Teaching Hospital in New Jersey.

What happens when the biggest stars in the world get too high on the Hollywood hog? When their bank accounts start swelling bigger than their heads? Master prankster Ashton Kutcher is there to punk 'em down to earth.