Host Neil deGrasse Tyson brings together celebrities, scientists and comedians to explore a variety of cosmic topics and collide pop culture with science in a way that late-night television has never seen before. Weekly topics range from popular science fiction, space travel, extraterrestrial life, the Big Bang, to the future of Earth and the environment. Tyson is an astrophysicist with a gifted ability to connect with everyone, inspiring us all to to "keep looking up."

Set in Charlotte, N.C., the story opens with everyone desperate to solve the latest crisis: a serial killer is specializing in out-of-town businessmen. Hammer and West make the murder investigation their top priority. But West is less than pleased when Hammer pairs her up with Brazil, a cub reporter assigned to cover the police department.

A detective uncovers a sinister conspiracy when he is sent to research a disintegrating neighborhood for a public relations campaign.

Detective Win Garano is asked to reopen a twenty-year-old murder case, and soon finds himself endangered by the political ambitions of a district attorney.

Bestselling crime writer Patricia Cornwell has set herself her toughest assignment yet - discovering the true identity of Jack the Ripper, widely seen as the world's first serial killer. Cornwell applies 21st Century scientific methods to these century-old crimes and is now convinced she knows the Ripper's identity. But how will her evidence be received?