Dr. Megan Hunt was in a class of her own, a brilliant neurosurgeon at the top of her game. But her world is turned upside down when a devastating car accident puts an end to her time in the operating room. Megan resumes her career as a medical examiner, determined to solve the puzzle of who or what killed the victims.

With a cosmic explosion threatening Earth's existence, the residents of the picturesque small town of Milford have taken their lives to the extreme: quitting jobs, indulging vices and basically living as if today were their last. The Montgomery family is no exception. Janet Montgomery's husband abandoned his family to climb the seven largest peaks in the world, her daughter Lydia has taken up witchcraft to help save the Earth and her 17 year old son Alex gets involved with the older next door neighbor.