Bizarre things start happening in the little New Mexico town where UFOs were spotted in 1947. Cut to 1999, when a cute high-school student saves the life of a teenage waitress. Surrounded by cliques of clever, angst-filled classmates, the two form a bond that threatens the survival of a secret universe involving superhuman powers, a yen for hot sauce and an alien gene pool.

A suburban housewife learns that she has psychic connections to a serial killer, and can predict this person's motives through her dreams.

While attending a Hollywood premiere with a famous action star, a crazed fan pulls a gun—but her movie hunk turns into a coward, and it's Vallery who becomes the hero. Suddenly, she's thrown into a world of action and danger as owner of a Hollywood protection agency, Vallery Irons Protection (V.I.P.), taking risks to protect others at a price few are willing to pay.

A brothel owner finds herself the target of an assassin.

The exploits of FBI Special Agents Fox Mulder and Dana Scully who investigate X-Files: marginalized, unsolved cases involving paranormal phenomena. Mulder believes in the existence of aliens and the paranormal while Scully, a skeptic, is assigned to make scientific analyses of Mulder's discoveries that debunk Mulder's work and thus return him to mainstream cases.

Follow the lives of a group of young adults living in a brownstone apartment complex on Melrose Place, in Los Angeles, California.