The exploits of FBI Special Agents Fox Mulder and Dana Scully who investigate X-Files: marginalized, unsolved cases involving paranormal phenomena. Mulder believes in the existence of aliens and the paranormal while Scully, a skeptic, is assigned to make scientific analyses of Mulder's discoveries that debunk Mulder's work and thus return him to mainstream cases.

After federal agent Cleopatra Jones orders the burning of a Turkish poppy field, the notorious drug lord Mommy vows to destroy her.

An alien is dispatched from a faraway galaxy to take over the Earth by "duplicating" humans and creating a race of zombies.