9-year-old Alex Pruitt is home alone with the chicken pox. Turns out, due to a mix-up among nefarious spies, Alex was given a toy car concealing a top-secret microchip. Now Alex must fend off the spies as they try to break into his house to get it back.

A transit worker pulls commuter Peter off railway tracks after he's mugged, but—while he's in a coma—his family mistakenly thinks she's Peter's fiancée, and she doesn't correct them. Things get more complicated when she falls for his brother, who's not quite sure that she's who she claims to be.

ER explores the inner workings of an urban teaching hospital and the critical issues faced by the dedicated physicians and staff of its overburdened emergency room.