Destination X (2006) was a professional wrestling pay-per-view (PPV) event produced by Total Nonstop Action Wrestling (TNA), which took place on March 12, 2006 from the TNA Impact! Zone in Orlando, Florida. It was the second event under the Destination X chronology. Eight matches were featured on the event's card.

IMPACT WRESTLING offers a unique style of wrestling that features a blend of the traditional with high flying athleticism and cutting edge action. IMPACT's roster includes the biggest names in wrestling today, and the hottest new stars in the sport.