In late 19th century Montana, an artist seeking inspiration explores the landscape with his Native American guide, and finds his conceptions of himself and of the world around him challenged. In 1970s Barstow, California, a questioning youth's mundane existence is given a shot of adrenaline by the arrival of a new exchange student who envelops them within her own lust for life. In present-day Wyoming, a trans teenager works through his self-destructive feelings with his perceptive, non-binary therapist.

Close to Home is an American crime drama television series co-produced by Warner Bros. Television and Jerry Bruckheimer Television for CBS.

Network television executive Gavin hopes to reunite celebrated Hollywood stars Piper Grayson, Kate Westbourne, and Addie Holden in a TV special after their 1960s movie musical Boy Crazy is re-released. Though the three women share the same agent, Gavin's seemingly insurmountable obstacle is that they all cannot stand each other.

Can you tell the difference between fact and fiction? Several stories of strange, mysterious and incredible occurrences are chronicled during each episode. It is up to the viewer to decide which stories actually happened and which were completely fabricated by the show’s writers. The answer is revealed by Jonathan Frakes at the conclusion of each episode.