Hollyoaks Later is a spin-off from the Channel 4 soap Hollyoaks. Broadcast on E4 with a late night slot, the series began in 2008, and was an annual event for the soap until 2013, when there was a break, until it returned with a special episode in 2020. Each of the original series was shown over five consecutive nights. The late night airing allowed for more sexual content, "edgier" storylines, and stronger language. Each series is a stand-alone story, although each ties in with events on the main show at the time, with the producers often taking advantage of the later broadcast time to tie up loose ends on the more violent and controversial storylines.

Two teens with special powers solve mysteries: Mark has the ability to read minds, while Song Li has the ability to read feelings. They are in a project run by Professor Henry Powers, who experiments with kids with special powers like the ones Mark and Song Li have. The professor's first experiment was Dr. Mary Holland, who helps Mark and Song Li solve the mysteries with Professor Powers.