Like any other day, French Prime Minister Lionel Jopsin was about to go to Matignon but his driver is missing! He drives the car himself only to find out that every street of Paris is empty, everyone is gone!

At a dysfunctional hospital in Paris, three bumbling, eccentric medical employees embark on zany misadventures with surgical imprecision.

The love affairs of Bob, a womanizer and seducer and Mammouth, the unhappy loner.