Homicide detective Tess Avery, diagnosed as blind, teams up with Sunny Patel, a remote guide, to solve crimes. Using tech and trust, they tackle cases while challenging notions of ability and boundaries.

After being struck by lightning, CSI investigator Barry Allen awakens from a nine-month coma to discover he has been granted the gift of super speed. Teaming up with S.T.A.R. Labs, Barry takes on the persona of The Flash, the Fastest Man Alive, to protect his city.

Spoiled billionaire playboy Oliver Queen is missing and presumed dead when his yacht is lost at sea. He returns five years later a changed man, determined to clean up the city as a hooded vigilante armed with a bow.

FBI Special Agent Olivia Dunham, brilliant but formerly institutionalized scientist Walter Bishop and his scheming, reluctant son Peter uncover a deadly mystery involving a series of unbelievable events and realize they may be a part of a larger, more disturbing pattern that blurs the line between science fiction and technology.

4400 centers on the return of 4400 people who, previously presumed dead or reported missing, reappear on Earth. Though they have not aged physically, some of them seem to have deeper alterations ranging from superhuman strength to an unexplained healing touch. A government agency is formed to track the 4400 people after one of them commits a murder.

A girl meets up with a guy for a weekend of talk and action, with complex revelations of character occurring in the rather strange situations in which they find themselves.