Physical therapist Leslie Wright lands the dream job of working with basketball superstar Scott McKnight, helping him recover from a career-threatening injury. All goes well and soon Leslie finds herself falling in love with him. Just as their friendship deepens, however, Scott focuses his attention back on his tenuous relationship with his ex-fiancé Morgan, Leslie's gorgeous godsister, who would love to be the basketball player's trophy wife.

Will Montgomery, a U.S. Army Staff Sergeant who has returned home from Iraq, is assigned to the Army’s Casualty Notification service. Montgomery is partnered with Captain Tony Stone, to give notice to the families of fallen soldiers. The Sergeant is drawn to Olivia Pitterson, to whom he has delivered news of her husband’s death.

Whatever Works explores the relationship between a crotchety misanthrope, Boris and a naïve, impressionable young runaway from the south, Melody. When Melody's uptight parents arrive in New York to rescue her, they are quickly drawn into wildly unexpected romantic entanglements. Everyone discovers that finding love is just a combination of lucky chance and appreciating the value of "whatever works."

In the criminal justice system, sexually-based offenses are considered especially heinous. In New York City, the dedicated detectives who investigate these vicious felonies are members of an elite squad known as the Special Victims Unit. These are their stories.