A destitute young Yoon Mi-so was brought up in an orphanage, but eventually found good fortune in the form of Lee Min-jae, a rich heir. But what appeared to be a storybook ending with her prince turns into tragedy when Min-jae divorces her. Cast away like a used toy, Mi-so hits her all-time low. But after a life of abandonment and betrayal, she finds love again.

Celebrity guests are split into two teams to compete in various contests. One guest, known only to himself, is designated the "X-Man", and does his best to cause his team to lose the contests. At the end, all guests try to determine the X-Man's identity.

Male and female contestants compete for "each other" in romance games. For example guests have to dance in order to impress the person they are after. Contestants are artists, actors, models, comedians, and MCs of the South Korean entertainment industry.

진주 목걸이는 KBS 2TV에서 2003년 9월 20일부터 2004년 3월 14일까지 매주 토,일 저녁 19시 55분에 방영되었던 주말 드라마이다.