Eccentric consulting detective Sherlock Holmes and Doctor John Watson battle to bring down a new nemesis and unravel a deadly plot that could destroy England.

Orphan Mary Katherine Gallagher, an ugly duckling at St. Monica High School, has a dream: to be kissed soulfully. She decides she can realize this dream if she becomes a superstar, so her prayers, her fantasies and her conversations with her only friend focus on achieving super-stardom.